Fastest way to get (const) pointer to struct for inter-operability with C/C++

It does not make a copy, as far as I know. According to the documentation, it

Invokes the given closure with a pointer to the given argument.

Compare also Allow let-to-pointer conversions, where it is said that

Therefore

let result = withUnsafePointer(to: actual_data, { some_c_function($0)} )

should be what you are looking for.